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A Week of Losses for Alnylam Pharmaceuticals: What the Chart and the News Say

By Wealth Awesome -

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Stocks & ETFs:ALNY.US

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Alnylam Pharmaceuticals Inc experienced a significant decline of 11.9% this week.

Alnylam Pharmaceuticals Inc saw its stock price fall by 11.9% over the past week, closing at US$224.39. This decline continues a downward trend for the company, which has lost 44.04% year-to-date. The stock's performance reflects a challenging environment, with a 1-month decline of 15.85% and a current position within 9% of its 52-week range of US$197.81 to US$495.55.

Investor takeaway: Investors should monitor upcoming developments as the company's stock continues to show volatility.

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Alnylam Pharmaceuticals Inc

ALNY.US

Full stock page →

ALNY.US

Alnylam Pharmaceuticals Inc

Source:WealthAwesomeWealthAwesome
↓ $86.41 (-27.79%)
120 day period
$205.48$264.49$323.50Apr 20Jul 16Oct 8

Market cap

$30.03B

P/E

37.8x

52W high

$495.55

52W low

$197.81

1W change

-2.88%

Beta

0.27

Analyst Price Targets

Based on 29 analysts covering ALNY · as of Oct 5, 2026

📈

Wall Street analysts forecast ALNY stock price to rise 65.3% over the next 12 months.

Consensus

Buy

4.31 / 5.00

Avg. Target

C$371.12

+65.3% Upside

Current Price

C$224.53

Last close

Analyst Breakdown (29 analysts)

Strong Buy 16
Buy 6
Hold 7
Compare analyst targets →

Targets are snapshotted when they change. Unchanged figures keep their original date. Not financial advice.

Wealth Awesome Price Forecast

WA Model

Statistical 90-day price range based on ALNY's historical volatility

HistoricalForecast68%95%
C$105.30C$151.18C$197.05C$242.92C$288.80C$334.67TodayJun 2Aug 6Oct 8Nov 20Jan 3Feb 15

30-Day Vol

45.9%

Annualized

90-Day Vol

70.8%

Annualized

Trend (90d)

-50.0%

Annualized drift

90d Mean

C$187.81

Expected price

HorizonExpected68% Range (1σ)
30 trading daysC$211.56C$180.59 – C$247.82
60 trading daysC$199.33C$159.36 – C$249.32
90 trading daysC$187.81C$142.79 – C$247.03

Methodology: Range is calculated using 30-day realized volatility via geometric Brownian motion (log-normal model). 68% band = ±1σ, 95% band = ±2σ. This is a statistical model, not a prediction. Past volatility does not guarantee future results. Not financial advice.

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Alnylam Stock Down 11.9% This Week

The stock's latest volume was 1,941 shares, significantly lower than the 20-day average volume of 1,384,283 shares.

Bull case

Analysts have an average target price of US$371.12, indicating potential upside from current levels. This suggests that despite recent struggles, there may be room for recovery as market conditions change.

Bear case

The stock has not only declined significantly over the past week but also shows a downward trend compared to its 50-day and 200-day moving averages. This indicates ongoing bearish sentiment among investors, raising concerns about further declines in the near term.

Stock Performance Overview

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This week, Alnylam Pharmaceuticals' stock experienced a decline of 11.9%, closing at US$224.39. The stock has been on a downward trajectory, with a 1-month loss of 15.85% and a year-to-date decline of 44.04%. The latest trading volume was 1,941 shares, which is significantly below the 20-day average of 1,384,283 shares, indicating reduced investor activity. The stock's beta is 0.27, suggesting lower volatility compared to the broader market.

Market Context and Technical Indicators

Alnylam's stock is currently trading below both its 50-day moving average of US$241.49 and its 200-day moving average of US$302.88, by 7.1% and 25.9% respectively. This positioning suggests persistent bearish sentiment among investors. The stock is currently within 9% of its 52-week range, reflecting a challenging environment. Despite the recent losses, the average analyst target price stands at US$371.12, indicating a potential upside of 65.4% from the current trading levels.

Future Considerations

Looking ahead, investors will be keen to observe any news or developments that may impact Alnylam's operations or market perception. The company's profit margin stands at 16.1%, and its return on equity is a strong 96.6%, suggesting robust underlying performance metrics that could influence future stock performance. With a P/E ratio of 37.08, the stock remains relatively high-valued compared to its earnings, prompting scrutiny as it continues to experience volatility.

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Wealth Awesome
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This content has been reviewed by CFA® charterholders and Certified Financial Planners (CFP®) with over a decade of experience in Canadian financial markets. All information is fact-checked against official Canadian sources and regulations.

Why these credentials matter: CFA® charterholders complete 900+ hours of rigorous study in investment analysis and ethics. CFP® professionals are held to the highest standards of financial planning competency and fiduciary duty in Canada.

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⚠️ Professional Disclaimer

This content is for educational purposes only and should not be considered personalized financial advice. While our team brings professional expertise, individual circumstances vary. For personalized guidance, consult with a qualified financial advisor, tax professional, or mortgage specialist.

Published: October 7, 2026
Last Updated: October 9, 2026

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