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Stocks/NASDAQ/KPTI

Karyopharm Therapeutics Inc (KPTI : NASDAQ)

Common Stock

$0.83

USD

+0.35 (73.35%)

Last updated: 2026-10-28

Follow KPTI

KPTI

Karyopharm Therapeutics Inc

Source:WealthAwesomeWealthAwesome
↓ $0.96 (-53.51%)
30 day period
$0.32$1.10$1.88Sep 17Oct 8Oct 28

Performance

1 Day

+73.35%

1 Week

+96.07%

1 Month

-48.64%

YTD

-91.15%

Key Statistics

Market Cap

$18.87M

52W High

$10.99

52W Low

$0.31

P/E Ratio

-

50 Day MA

$1.27

200 Day MA

$6.10

Beta

1.04

Dividend Yield

-

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Technical Indicators

Price vs 50-Day SMA

↓Below 50 SMA

Price vs 200-Day SMA

↓Below 200 SMA

Recent Price History

DateOpenHighLowCloseAdj CloseVolume
10/28/2026$0.46$0.91$0.46$0.83$0.8352,782,079
10/27/2026$0.46$0.48$0.43$0.48$0.48996,614
10/26/2026$0.51$0.52$0.42$0.48$0.481,363,766
10/23/2026$0.54$0.56$0.44$0.52$0.521,959,000
10/22/2026$0.44$0.55$0.42$0.55$0.557,287,547
10/21/2026$0.36$0.44$0.36$0.42$0.421,538,271
10/20/2026$0.34$0.39$0.34$0.36$0.36761,154
10/19/2026$0.40$0.40$0.33$0.35$0.351,247,202
10/16/2026$0.35$0.40$0.33$0.39$0.392,707,000
10/15/2026$0.31$0.35$0.31$0.35$0.351,321,959

Analyst Price Targets

Based on 5 analysts covering KPTI · as of Oct 5, 2026

📈

Wall Street analysts forecast KPTI stock price to rise 771.3% over the next 12 months.

Consensus

Buy

4.20 / 5.00

Avg. Target

US$7.25

+771.3% Upside

Current Price

US$0.83

Last close

Analyst Breakdown (5 analysts)

Strong Buy 2
Buy 2
Hold 1
Compare analyst targets →

Targets are snapshotted when they change. Unchanged figures keep their original date. Not financial advice.

Wealth Awesome Price Forecast

WA Model

Statistical 90-day price range based on KPTI's historical volatility

HistoricalForecast68%95%
US$0.03US$3.63US$7.23US$10.84US$14.44US$18.05TodayJun 23Aug 26Oct 28Dec 10Jan 23Mar 7

30-Day Vol

269.9%

Annualized

90-Day Vol

276.0%

Annualized

Trend (90d)

-50.0%

Annualized drift

90d Mean

US$0.70

Expected price

HorizonExpected68% Range (1σ)
30 trading daysUS$0.78US$0.31 – US$1.99
60 trading daysUS$0.74US$0.20 – US$2.76
90 trading daysUS$0.70US$0.14 – US$3.49

Methodology: Range is calculated using 30-day realized volatility via geometric Brownian motion (log-normal model). 68% band = ±1σ, 95% band = ±2σ. This is a statistical model, not a prediction. Past volatility does not guarantee future results. Not financial advice.

About Karyopharm Therapeutics Inc

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compounds include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also develops Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating other myeloproliferative neoplasms and TP53 wild-type solid tumors. In addition, the company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, the company has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed or refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Financials

Revenue (TTM)
$146.62M
EBITDA
$-82.20M
Profit Margin
-153.28%
ROE (TTM)
-891.05%
EPS (Diluted)
-14.33
Book Value
-14.56

Classification

Sector
Health Care
Industry
Biotechnology
Group
Pharmaceuticals, Biotechnology & Life Sciences

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Common Questions About KPTI.US

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