Canadian Companies with Highest Profit Margins — Health Care
Net profit margin ranking for TSX and TSXV companies.
Updated September 23, 2026174 companiesTotal market cap $1624.6B
Showing 174 companies (CDRs hidden)
| Rank | Company | Symbol | Market Cap | Revenue (TTM) | Profit Margin |
|---|---|---|---|---|---|
| 1 | Daxor Corporation | DXR:US | $66M | $31,360 | 19861.41% |
| 2 | Rallybio Corp | RLYB:US | $90M | $646,000 | 7051.24% |
| 3 | Kyntra Bio, Inc. | KYNB:US | $29M | $5M | 3968.63% |
| 4 | Hyperion DeFi, Inc. | HYPD:US | $60M | $1M | 474.87% |
| 5 | Elutia Inc. | ELUT:US | $36M | $12M | 426.90% |
| 6 | Omeros Corporation | OMER:US | $1.5B | $38M | 324.88% |
| 7 | NewGenIvf Group Limited Class A Ordinary Shares | NIVF:US | $2M | $5M | 209.03% |
| 8 | Fortress Biotech Inc | FBIO:US | $80M | $68M | 163.32% |
| 9 | Fortress Biotech Inc Pref Series A | FBIOP:US | $78M | $68M | 163.32% |
| 10 | Rigel Pharmaceuticals Inc | RIGL:US | $912M | $277M | 116.30% |
| 11 | Aurinia Pharmaceuticals Inc | AUPH:US | $2.2B | $312M | 100.84% |
| 12 | Standard Biotools Inc | LAB:US | $291M | $85M | 100.37% |
| 13 | Arbutus Biopharma Corp | ABUS:US | $991M | $182M | 84.23% |
| 14 | Innoviva Inc | INVA:US | $1.5B | $440M | 81.19% |
| 15 | Anbio Biotechnology Class A Ordinary Shares | NNNN:US | $245M | $9M | 74.06% |
| 16 | Ascendis Pharma AS | ASND:US | $15.6B | $1.0B | 70.85% |
| 17 | Agenus Inc | AGEN:US | $376M | $133M | 69.34% |
| 18 | Ligand Pharmaceuticals Incorporated | LGND:US | $5.8B | $291M | 67.88% |
| 19 | Q32 Bio Inc | QTTB:US | $315M | $54M | 62.87% |
| 20 | Lakefront Biotherapeutics NV | LKFT:US | $1.9B | $991M | 60.23% |
| 21 | Cipher Pharmaceuticals Inc | CPH:TO | $369M | $50M | 58.42% |
| 22 | LENSAR Inc | LNSR:US | $89M | $60M | 57.57% |
| 23 | TG Therapeutics Inc | TGTX:US | $8.9B | $800M | 55.22% |
| 24 | Krystal Biotech Inc | KRYS:US | $9.9B | $440M | 54.82% |
| 25 | BioLife Solutions Inc | BLFS:US | $1.8B | $107M | 54.35% |
| 26 | Theravance Biopharma Inc | TBPH:US | $885M | $104M | 51.58% |
| 27 | Compugen | CGEN:US | $231M | $74M | 47.56% |
| 28 | Zevra Therapeutics Inc. | ZVRA:US | $688M | $136M | 42.82% |
| 29 | United Therapeutics Corporation | UTHR:US | $21.3B | $3.2B | 41.56% |
| 30 | CorMedix Inc | CRMD:US | $606M | $462M | 40.49% |
| 31 | Cronos Group Inc | CRON:US | $1.3B | $179M | 39.08% |
| 32 | Cronos Group Inc | CRON:TO | $1.8B | $179M | 39.08% |
| 33 | Exelixis Inc | EXEL:US | $14.4B | $2.4B | 35.33% |
| 34 | Vertex Pharmaceuticals Inc | VRTX:US | $130.4B | $12.6B | 35.00% |
| 35 | SANUWAVE Health, Inc. Common Stock | SNWV:US | $38M | $44M | 34.66% |
| 36 | ACADIA Pharmaceuticals Inc | ACAD:US | $4.6B | $1.1B | 33.42% |
| 37 | Ironwood Pharmaceuticals Inc | IRWD:US | $729M | $389M | 33.36% |
| 38 | ADMA Biologics Inc | ADMA:US | $2.2B | $512M | 32.98% |
| 39 | argenx NV ADR | ARGX:US | $61.5B | $5.3B | 32.27% |
| 40 | Royalty Pharma Plc | RPRX:US | $33.8B | $2.5B | 32.02% |
| 41 | Liquidia Technologies Inc | LQDA:US | $6.1B | $451M | 30.74% |
| 42 | Protagonist Therapeutics Inc | PTGX:US | $9.4B | $282M | 29.40% |
| 43 | Utah Medical Products Inc | UTMD:US | $244M | $36M | 29.04% |
| 44 | Intuitive Surgical Inc | ISRG:US | $143.9B | $11.0B | 28.45% |
| 45 | OrganiGram Holdings Inc | OGI:TO | $226M | $309M | 28.02% |
| 46 | OrganiGram Holdings Inc | OGI:US | $160M | $309M | 28.02% |
| 47 | SBC Medical Group Holdings Incorporated | SBC:US | $518M | $175M | 27.99% |
| 48 | Regeneron Pharmaceuticals Inc | REGN:US | $82.2B | $15.5B | 27.87% |
| 49 | Incyte Corporation | INCY:US | $25.3B | $5.8B | 27.71% |
| 50 | Indivior PLC Ordinary Shares | INDV:US | $4.3B | $1.3B | 26.75% |
| 51 | Iradimed Co | IRMD:US | $1.1B | $86M | 26.70% |
| 52 | IDEXX Laboratories Inc | IDXX:US | $40.6B | $4.6B | 25.03% |
| 53 | LeMaitre Vascular Inc | LMAT:US | $1.9B | $262M | 25.02% |
| 54 | Halozyme Therapeutics Inc | HALO:US | $12.6B | $1.7B | 24.86% |
| 55 | YD Bio Ltd | YDES:US | $186M | $1M | 24.67% |
| 56 | CareDx Inc | CDNA:US | $2.8B | $458M | 24.23% |
| 57 | Amgen Inc | AMGN:US | $212.6B | $38.1B | 22.95% |
| 58 | TransMedics Group Inc | TMDX:US | $3.0B | $668M | 22.69% |
| 59 | Check-Cap Ltd. | MBAI:US | $95M | $2M | 21.75% |
| 60 | Sinovac Biotech Ltd | SVA:US | $642M | $511M | 21.61% |
| 61 | Nutex Health Inc | NUTX:US | $1.4B | $847M | 21.25% |
| 62 | Neurocrine Biosciences Inc | NBIX:US | $14.5B | $3.4B | 20.91% |
| 63 | InMode Ltd | INMD:US | $832M | $375M | 20.69% |
| 64 | Jazz Pharmaceuticals PLC | JAZZ:US | $15.6B | $4.6B | 20.45% |
| 65 | Veracyte Inc | VCYT:US | $3.5B | $562M | 20.37% |
| 66 | DexCom Inc | DXCM:US | $33.8B | $5.0B | 20.12% |
| 67 | MeiraGTx Holdings PLC | MGTX:US | $1.2B | $398M | 19.87% |
| 68 | Auxly Cannabis Group Inc | XLY:TO | $380M | $166M | 19.69% |
| 69 | Agilent Technologies Inc | A:US | $43.3B | $7.4B | 19.53% |
| 70 | Genmab AS | GMAB:US | $21.7B | $4.1B | 19.08% |
| 71 | Harmony Biosciences Holdings | HRMY:US | $2.4B | $960M | 18.88% |
| 72 | Illumina Inc | ILMN:US | $37.4B | $4.5B | 18.34% |
| 73 | Biosyent Inc. | RX:V | $181M | $56M | 17.73% |
| 74 | Lantheus Holdings Inc | LNTH:US | $6.5B | $1.6B | 17.69% |
| 75 | Medpace Holdings Inc | MEDP:US | $17.4B | $2.8B | 17.67% |
| 76 | Pro-Dex Inc | PDEX:US | $232M | $78M | 17.62% |
| 77 | HealthEquity Inc | HQY:US | $7.8B | $1.4B | 17.36% |
| 78 | Alnylam Pharmaceuticals Inc | ALNY:US | $32.7B | $4.8B | 16.13% |
| 79 | Spero Therapeutics Inc | SPRO:US | $66M | $47M | 15.71% |
| 80 | Brainsway Ltd | BWAY:US | $548M | $61M | 15.56% |
| 81 | Bio-Techne Corp | TECH:US | $11.4B | $1.2B | 14.97% |
| 82 | Medical Facilities Corporation | DR:TO | $244M | $265M | 14.57% |
| 83 | NexgenRX Inc. | NXG:V | $43M | $19M | 13.60% |
| 84 | The Cooper Companies, Inc | COO:US | $10.5B | $4.2B | 13.46% |
| 85 | Sotera Health Co | SHC:US | $5.3B | $1.2B | 13.44% |
| 86 | LivaNova PLC | LIVN:US | $4.3B | $1.5B | 12.81% |
| 87 | Covalon Technologies Ltd. | COV:V | $110M | $34M | 12.78% |
| 88 | Niagen Bioscience, Inc. | NAGE:US | $241M | $129M | 12.39% |
| 89 | Insulet Corporation | PODD:US | $9.7B | $3.1B | 12.29% |
| 90 | Eton Pharmaceuticals Inc | ETON:US | $1.6B | $106M | 12.02% |
| 91 | CorVel Corp | CRVL:US | $3.7B | $984M | 11.72% |
| 92 | Kamada | KMDA:US | $512M | $192M | 11.60% |
| 93 | Puma Biotechnology Inc | PBYI:US | $507M | $231M | 11.55% |
| 94 | UFP Technologies Inc | UFPT:US | $2.2B | $632M | 11.45% |
| 95 | Waystar Holding Corp. Common Stock | WAY:US | $4.9B | $1.2B | 11.18% |
| 96 | ANI Pharmaceuticals Inc | ANIP:US | $1.8B | $978M | 11.07% |
| 97 | Amphastar P | AMPH:US | $1.0B | $730M | 10.76% |
| 98 | BeiGene, Ltd. | ONC:US | $41.6B | $6.1B | 10.70% |
| 99 | Caris Life Sciences, Inc. Common Stock | CAI:US | $8.7B | $990M | 10.62% |
| 100 | Aveanna Healthcare Holdings Inc | AVAH:US | $2.9B | $2.6B | 10.56% |
| 101 | Cannara Biotech Inc | LOVE:V | $181M | $112M | 10.52% |
| 102 | Align Technology Inc | ALGN:US | $10.4B | $4.1B | 9.99% |
| 103 | Simulations Plus Inc | SLP:US | $373M | $82M | 9.88% |
| 104 | Kiniksa Pharmaceuticals Ltd | KNSA:US | $6.1B | $841M | 9.59% |
| 105 | Bioventus Inc | BVS:US | $909M | $582M | 9.36% |
| 106 | GE HealthCare Technologies Inc. | GEHC:US | $29.9B | $21.3B | 9.33% |
| 107 | Merit Medical Systems Inc | MMSI:US | $5.2B | $1.6B | 9.22% |
| 108 | Embecta Corp | EMBC:US | $300M | $1.0B | 8.59% |
| 109 | Hydreight Technologies Inc | NURS:V | $171M | $78M | 8.59% |
| 110 | BillionToOne, Inc. Class A Common Stock | BLLN:US | $4.9B | $397M | 8.35% |
| 111 | Biogen Inc | BIIB:US | $33.3B | $10.0B | 8.32% |
| 112 | Sanofi ADR | SNY:US | $101.8B | $48.9B | 8.09% |
| 113 | Vericel Corp Ord | VCEL:US | $2.0B | $306M | 7.91% |
| 114 | Sucro Limited | SUGR:V | $228M | $561M | 7.16% |
| 115 | Addus HomeCare Corporation | ADUS:US | $2.1B | $1.5B | 7.13% |
| 116 | CareRx Corp | CRRX:TO | $201M | $377M | 7.13% |
| 117 | Tactile Systems Technology Inc | TCMD:US | $518M | $350M | 7.10% |
| 118 | The Ensign Group Inc | ENSG:US | $10.3B | $5.5B | 6.90% |
| 119 | Corcept Therapeutics Incorporated | CORT:US | $12.7B | $831M | 6.64% |
| 120 | HealthStream Inc | HSTM:US | $890M | $321M | 6.60% |
| 121 | Phibro Animal Health Corporation | PAHC:US | $1.4B | $1.5B | 6.57% |
| 122 | The Joint Corp | JYNT:US | $120M | $59M | 6.49% |
| 123 | CareCloud, Inc. | CCLD:US | $91M | $129M | 6.21% |
| 124 | Arcutis Biotherapeutics Inc | ARQT:US | $3.3B | $464M | 6.15% |
| 125 | Extendicare Inc | EXE:TO | $3.0B | $2.0B | 6.13% |
| 126 | Grifols SA ADR | GRFS:US | $5.0B | $7.4B | 6.09% |
| 127 | Progyny Inc | PGNY:US | $2.0B | $1.3B | 6.00% |
| 128 | JIN MEDICAL INTERNATIONAL LTD. Ordinary Shares | ZJYL:US | $155M | $20M | 5.95% |
| 129 | Collegium Pharmaceutical Inc | COLL:US | $714M | $808M | 5.93% |
| 130 | Vitalhub Corp | VHI:TO | $473M | $127M | 5.89% |
| 131 | Element Lifestyle Retirement Inc | ELM:V | $1M | $1M | 5.32% |
| 132 | Repligen Corporation | RGEN:US | $10.5B | $785M | 5.29% |
| 133 | Amneal Pharmaceuticals, Inc. Class A Common Stock | AMRX:US | $6.8B | $3.1B | 5.05% |
| 134 | Sienna Senior Living Inc | SIA:TO | $2.3B | $1.1B | 4.82% |
| 135 | Viemed Healthcare Inc | VMD:US | $341M | $302M | 4.81% |
| 136 | OPTIMIZERx Corp | OPRX:US | $144M | $99M | 4.66% |
| 137 | National Research Corp | NRC:US | $484M | $140M | 4.18% |
| 138 | Nova Leap Health Corp | NLH:V | $47M | $34M | 4.01% |
| 139 | Alkermes Plc | ALKS:US | $7.3B | $1.7B | 3.97% |
| 140 | Telix Pharmaceuticals Limited | TLX:US | $3.8B | $891M | 3.76% |
| 141 | Option Care Health Inc | OPCH:US | $3.6B | $5.7B | 3.68% |
| 142 | HUTCHMED DRC | HCM:US | $2.5B | $549M | 3.26% |
| 143 | biote Corp | BTMD:US | $45M | $184M | 3.19% |
| 144 | Lifestance Health Group Inc | LFST:US | $4.8B | $1.6B | 3.19% |
| 145 | Omnicell Inc | OMCL:US | $1.5B | $1.2B | 3.14% |
| 146 | Kewaunee Scientific Corporation | KEQU:US | $99M | $277M | 2.97% |
| 147 | Henry Schein Inc | HSIC:US | $9.5B | $13.6B | 2.96% |
| 148 | Arvinas Inc | ARVN:US | $549M | $317M | 2.94% |
| 149 | Pennant Group Inc | PNTG:US | $1.4B | $1.1B | 2.93% |
| 150 | ImmuCell Corporation | ICCC:US | $91M | $31M | 2.57% |
| 151 | Varex Imaging Corp | VREX:US | $778M | $865M | 2.56% |
| 152 | BrightSpring Health Services, Inc. Common Stock | BTSG:US | $11.2B | $14.4B | 2.55% |
| 153 | Pharming Group NV | PHAR:US | $765M | $366M | 2.54% |
| 154 | Medline Inc. Class A Common Stock | MDLN:US | $43.0B | $29.9B | 2.32% |
| 155 | Biomarin Pharmaceutical Inc | BMRN:US | $12.4B | $3.4B | 2.14% |
| 156 | Goodrx Holdings Inc | GDRX:US | $1.2B | $785M | 2.07% |
| 157 | Pacira BioSciences, Inc. | PCRX:US | $985M | $746M | 1.96% |
| 158 | Mesa Laboratories Inc | MLAB:US | $753M | $250M | 1.92% |
| 159 | AtriCure Inc | ATRC:US | $3.0B | $570M | 1.85% |
| 160 | MiMedx Group Inc | MDXG:US | $702M | $355M | 1.76% |
| 161 | NeuPath Health Inc | NPTH:V | $30M | $89M | 1.51% |
| 162 | ICU Medical Inc | ICUI:US | $4.0B | $2.2B | 1.39% |
| 163 | Omada Health, Inc. Common Stock | OMDA:US | $1.3B | $310M | 1.39% |
| 164 | rYojbaba Co., Ltd. Common Shares | RYOJ:US | $46M | $9M | 1.28% |
| 165 | Privia Health Group Inc | PRVA:US | $2.5B | $2.4B | 1.19% |
| 166 | STAAR Surgical Company | STAA:US | $1.0B | $340M | 1.13% |
| 167 | Astrana Health Inc | ASTH:US | $1.7B | $3.8B | 1.06% |
| 168 | Alignment Healthcare LLC | ALHC:US | $1.7B | $4.6B | 0.89% |
| 169 | Delcath Systems Inc | DCTH:US | $559M | $95M | 0.56% |
| 170 | Medirom Healthcare Technologies Inc | MRM:US | $6M | $8.1B | 0.50% |
| 171 | ICON PLC | ICLR:US | $12.9B | $8.3B | 0.33% |
| 172 | WELL Health Technologies Corp | WELL:TO | $1.1B | $1.5B | 0.25% |
| 173 | LifeMD Inc Preferred Series A | LFMDP:US | - | $192M | 0.11% |
| 174 | LifeMD Inc | LFMD:US | $155M | $192M | 0.11% |
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Frequently Asked Questions
Which Canadian company ranks #1 by profit margin in Health Care?
As of September 23, 2026, Daxor Corporation (DXR:US) ranks #1 in Health Care at 19861.41%.
How often is this ranking updated?
The table is rebuilt from live fundamentals throughout the day. This page currently shows data as of September 23, 2026.
How many companies are in this profit margin list?
This view shows 174 Canadian listings in Health Care. Canadian Depositary Receipts are hidden by default.
What is the difference between TSX and TSXV?
The Toronto Stock Exchange (TSX) lists larger established companies. The TSX Venture Exchange (TSXV) lists earlier-stage companies. Use the exchange filter to separate them.
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