Canadian Stocks with Highest Return on Assets (ROA) — Health Care

Return on assets ranking for Canadian public companies.

Updated October 14, 2026185 companiesTotal market cap $1883.8B

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Showing 185 companies (CDRs hidden)

Rank	Company	Symbol	Sector	Market Cap	ROA (TTM)
1	Aspire BioPharma, Inc.	ASBP:US	Health Care	$12M	60.58%
2	BioCryst Pharmaceuticals Inc	BCRX:US	Health Care	$2.2B	52.86%
3	Arbutus Biopharma Corp	ABUS:US	Health Care	$647M	48.84%
4	Ironwood Pharmaceuticals Inc	IRWD:US	Health Care	$631M	47.02%
5	MeiraGTx Holdings PLC	MGTX:US	Health Care	$997M	38.65%
6	Nutex Health Inc	NUTX:US	Health Care	$1.4B	33.32%
7	IDEXX Laboratories Inc	IDXX:US	Health Care	$40.8B	27.09%
8	Liquidia Technologies Inc	LQDA:US	Health Care	$2.5B	27.04%
9	Indivior PLC Ordinary Shares	INDV:US	Health Care	$4.3B	26.40%
10	Halozyme Therapeutics Inc	HALO:US	Health Care	$12.5B	25.49%
11	CorMedix Inc	CRMD:US	Health Care	$575M	24.56%
12	Exelixis Inc	EXEL:US	Health Care	$14.8B	23.97%
13	ADMA Biologics Inc	ADMA:US	Health Care	$2.3B	21.78%
14	Medpace Holdings Inc	MEDP:US	Health Care	$17.1B	20.10%
15	Check-Cap Ltd.	MBAI:US	Health Care	$50M	17.15%
16	Incyte Corporation	INCY:US	Health Care	$22.9B	16.83%
17	Biosyent Inc.	RX:V	Health Care	$193M	15.90%
18	Iradimed Co	IRMD:US	Health Care	$1.1B	15.56%
19	Aurinia Pharmaceuticals Inc	AUPH:US	Health Care	$2.2B	15.49%
20	Compugen	CGEN:US	Health Care	$202M	15.46%
21	Rigel Pharmaceuticals Inc	RIGL:US	Health Care	$912M	14.95%
22	Q32 Bio Inc	QTTB:US	Health Care	$248M	14.74%
23	CorVel Corp	CRVL:US	Health Care	$3.9B	14.68%
24	Anbio Biotechnology Class A Ordinary Shares	NNNN:US	Health Care	$205M	14.66%
25	Gilead Sciences Inc	GILD:US	Health Care	$187.4B	14.09%
26	biote Corp	BTMD:US	Health Care	$39M	13.70%
27	Agenus Inc	AGEN:US	Health Care	$346M	12.53%
28	Alnylam Pharmaceuticals Inc	ALNY:US	Health Care	$31.1B	12.34%
29	Embecta Corp	EMBC:US	Health Care	$322M	12.24%
30	Pro-Dex Inc	PDEX:US	Health Care	$202M	11.97%
31	Vertex Pharmaceuticals Inc	VRTX:US	Health Care	$129.3B	11.93%
32	Eton Pharmaceuticals Inc	ETON:US	Health Care	$1.6B	11.86%
33	Hydreight Technologies Inc	NURS:V	Health Care	$195M	11.71%
34	Neurocrine Biosciences Inc	NBIX:US	Health Care	$14.4B	11.70%
35	argenx NV ADR	ARGX:US	Health Care	$51.9B	11.64%
36	Harmony Biosciences Holdings	HRMY:US	Health Care	$2.3B	11.62%
37	United Therapeutics Corporation	UTHR:US	Health Care	$23.6B	11.61%
38	Medical Facilities Corporation	DR:TO	Health Care	$241M	11.53%
39	Sinovac Biotech Ltd	SVA:US	Health Care	$642M	11.46%
40	SBC Medical Group Holdings Incorporated	SBC:US	Health Care	$554M	11.32%
41	Intuitive Surgical Inc	ISRG:US	Health Care	$149.8B	10.51%
42	DexCom Inc	DXCM:US	Health Care	$32.4B	10.33%
43	Progyny Inc	PGNY:US	Health Care	$2.2B	10.14%
44	Lakefront Biotherapeutics NV	LKFT:US	Health Care	$1.9B	9.93%
45	Puma Biotechnology Inc	PBYI:US	Health Care	$531M	9.81%
46	Insulet Corporation	PODD:US	Health Care	$9.7B	9.72%
47	Aveanna Healthcare Holdings Inc	AVAH:US	Health Care	$2.7B	9.69%
48	Ascendis Pharma AS	ASND:US	Health Care	$15.1B	9.58%
49	Jack Nathan Medical Corp	JNH:V	Health Care	$1M	9.45%
50	Krystal Biotech Inc	KRYS:US	Health Care	$9.8B	9.37%
51	Extendicare Inc	EXE:TO	Health Care	$2.5B	9.37%
52	UFP Technologies Inc	UFPT:US	Health Care	$2.2B	9.13%
53	Genmab AS	GMAB:US	Health Care	$23.0B	8.79%
54	Caris Life Sciences, Inc. Common Stock	CAI:US	Health Care	$8.4B	8.77%
55	Zevra Therapeutics Inc.	ZVRA:US	Health Care	$672M	8.74%
56	Illumina Inc	ILMN:US	Health Care	$41.8B	8.67%
57	Amgen Inc	AMGN:US	Health Care	$224.3B	8.67%
58	Agilent Technologies Inc	A:US	Health Care	$43.3B	8.63%
59	Sotera Health Co	SHC:US	Health Care	$5.2B	8.60%
60	Amneal Pharmaceuticals, Inc. Class A Common Stock	AMRX:US	Health Care	$7.0B	8.60%
61	Phibro Animal Health Corporation	PAHC:US	Health Care	$1.5B	8.48%
62	Lantheus Holdings Inc	LNTH:US	Health Care	$6.5B	8.38%
63	Viemed Healthcare Inc	VMD:US	Health Care	$363M	8.21%
64	National Research Corp	NRC:US	Health Care	$451M	8.13%
65	Kiniksa Pharmaceuticals Ltd	KNSA:US	Health Care	$6.1B	8.05%
66	Cipher Pharmaceuticals Inc	CPH:TO	Health Care	$347M	7.97%
67	Tactile Systems Technology Inc	TCMD:US	Health Care	$508M	7.92%
68	Sanara Medtech Inc	SMTI:US	Health Care	$323M	7.64%
69	Align Technology Inc	ALGN:US	Health Care	$10.0B	7.56%
70	Cannara Biotech Inc	LOVE:V	Health Care	$181M	7.51%
71	BeiGene, Ltd.	ONC:US	Health Care	$39.9B	7.46%
72	LeMaitre Vascular Inc	LMAT:US	Health Care	$1.8B	7.44%
73	TG Therapeutics Inc	TGTX:US	Health Care	$8.5B	7.28%
74	Spero Therapeutics Inc	SPRO:US	Health Care	$70M	7.19%
75	Auxly Cannabis Group Inc	XLY:TO	Health Care	$345M	6.98%
76	Innoviva Inc	INVA:US	Health Care	$1.5B	6.95%
77	Covalon Technologies Ltd.	COV:V	Health Care	$110M	6.87%
78	Jazz Pharmaceuticals PLC	JAZZ:US	Health Care	$14.2B	6.86%
79	CareCloud, Inc.	CCLD:US	Health Care	$82M	6.82%
80	AnaptysBio Inc	ANAB:US	Health Care	$1.4B	6.78%
81	Bio-Techne Corp	TECH:US	Health Care	$11.4B	6.67%
82	HealthEquity Inc	HQY:US	Health Care	$7.7B	6.65%
83	Bausch Health Companies Inc	BHC:TO	Health Care	$3.2B	6.57%
84	Regeneron Pharmaceuticals Inc	REGN:US	Health Care	$76.9B	6.53%
85	Addus HomeCare Corporation	ADUS:US	Health Care	$2.2B	6.27%
86	ImmuCell Corporation	ICCC:US	Health Care	$87M	6.25%
87	Element Lifestyle Retirement Inc	ELM:V	Health Care	$0M	6.25%
88	Option Care Health Inc	OPCH:US	Health Care	$4.7B	6.17%
89	InMode Ltd	INMD:US	Health Care	$818M	6.17%
90	Xeris Pharmaceuticals Inc	XERS:US	Health Care	$1.9B	6.13%
91	Utah Medical Products Inc	UTMD:US	Health Care	$236M	6.10%
92	Collegium Pharmaceutical Inc	COLL:US	Health Care	$719M	5.76%
93	STAAR Surgical Company	STAA:US	Health Care	$1.1B	5.65%
94	NexgenRX Inc.	NXG:V	Health Care	$43M	5.54%
95	SANUWAVE Health, Inc. Common Stock	SNWV:US	Health Care	$48M	5.51%
96	The Ensign Group Inc	ENSG:US	Health Care	$10.1B	5.49%
97	Bioventus Inc	BVS:US	Health Care	$892M	5.49%
98	Simulations Plus Inc	SLP:US	Health Care	$374M	5.48%
99	ANI Pharmaceuticals Inc	ANIP:US	Health Care	$1.7B	5.45%
100	Niagen Bioscience, Inc.	NAGE:US	Health Care	$214M	5.44%
101	Biogen Inc	BIIB:US	Health Care	$33.9B	5.21%
102	BillionToOne, Inc. Class A Common Stock	BLLN:US	Health Care	$4.6B	5.19%
103	GE HealthCare Technologies Inc.	GEHC:US	Health Care	$30.8B	5.13%
104	Amphastar P	AMPH:US	Health Care	$1.1B	5.11%
105	Kewaunee Scientific Corporation	KEQU:US	Health Care	$98M	5.10%
106	Sanofi ADR	SNY:US	Health Care	$96.0B	5.09%
107	Sucro Limited	SUGR:V	Health Care	$244M	5.09%
108	Arcutis Biotherapeutics Inc	ARQT:US	Health Care	$3.3B	5.09%
109	Royalty Pharma Plc	RPRX:US	Health Care	$32.9B	5.09%
110	LivaNova PLC	LIVN:US	Health Care	$4.2B	5.04%
111	TerrAscend Corp.	TSND:TO	Health Care	$270M	4.99%
112	Merit Medical Systems Inc	MMSI:US	Health Care	$5.2B	4.92%
113	BrightSpring Health Services, Inc. Common Stock	BTSG:US	Health Care	$12.5B	4.88%
114	Kamada	KMDA:US	Health Care	$466M	4.63%
115	Protagonist Therapeutics Inc	PTGX:US	Health Care	$9.3B	4.55%
116	Pennant Group Inc	PNTG:US	Health Care	$1.4B	4.50%
117	DRI Healthcare Trust	DHT-U:TO	Health Care	$703M	4.43%
118	DRI Healthcare Trust	DHT-UN:TO	Health Care	$1.0B	4.43%
119	Henry Schein Inc	HSIC:US	Health Care	$9.6B	4.39%
120	Nova Leap Health Corp	NLH:V	Health Care	$40M	4.37%
121	TransMedics Group Inc	TMDX:US	Health Care	$2.7B	4.33%
122	Grifols SA ADR	GRFS:US	Health Care	$5.1B	4.23%
123	OPTIMIZERx Corp	OPRX:US	Health Care	$155M	4.22%
124	Alkermes Plc	ALKS:US	Health Care	$6.8B	4.20%
125	Varex Imaging Corp	VREX:US	Health Care	$784M	4.15%
126	Veracyte Inc	VCYT:US	Health Care	$3.5B	4.09%
127	Brainsway Ltd	BWAY:US	Health Care	$474M	4.05%
128	Ligand Pharmaceuticals Incorporated	LGND:US	Health Care	$6.0B	3.99%
129	Astrana Health Inc	ASTH:US	Health Care	$1.9B	3.76%
130	Surgery Partners Inc	SGRY:US	Health Care	$1.8B	3.67%
131	ACADIA Pharmaceuticals Inc	ACAD:US	Health Care	$3.4B	3.64%
132	Acadia Healthcare Company Inc	ACHC:US	Health Care	$2.8B	3.57%
133	Pharming Group NV	PHAR:US	Health Care	$693M	3.47%
134	Waystar Holding Corp. Common Stock	WAY:US	Health Care	$5.1B	3.44%
135	CareRx Corp	CRRX:TO	Health Care	$208M	3.34%
136	NeuPath Health Inc	NPTH:V	Health Care	$31M	3.30%
137	Mesa Laboratories Inc	MLAB:US	Health Care	$714M	3.29%
138	Biomarin Pharmaceutical Inc	BMRN:US	Health Care	$10.6B	3.26%
139	HealthStream Inc	HSTM:US	Health Care	$1.0B	3.22%
140	Bruker Corporation	BRKR:US	Health Care	$9.0B	3.14%
141	Alignment Healthcare LLC	ALHC:US	Health Care	$1.6B	3.07%
142	Goodrx Holdings Inc	GDRX:US	Health Care	$1.2B	3.05%
143	Decibel Cannabis Company Inc	DB:V	Health Care	$923M	3.05%
144	Medexus Pharmaceuticals Inc	MDP:TO	Health Care	$156M	3.00%
145	Vitalhub Corp	VHI:TO	Health Care	$456M	2.90%
146	Integra LifeSciences Holdings	IART:US	Health Care	$1.0B	2.83%
147	Sienna Senior Living Inc	SIA:TO	Health Care	$2.1B	2.80%
148	The Cooper Companies, Inc	COO:US	Health Care	$10.3B	2.74%
149	Telix Pharmaceuticals Limited	TLX:US	Health Care	$3.8B	2.71%
150	Viatris Inc	VTRS:US	Health Care	$20.3B	2.67%
151	WELL Health Technologies Corp	WELL:TO	Health Care	$1.1B	2.65%
152	Medline Inc. Class A Common Stock	MDLN:US	Health Care	$48.8B	2.46%
153	PTC Therapeutics Inc	PTCT:US	Health Care	$5.3B	2.46%
154	Vericel Corp Ord	VCEL:US	Health Care	$2.1B	2.43%
155	The Joint Corp	JYNT:US	Health Care	$100M	2.33%
156	Lifestance Health Group Inc	LFST:US	Health Care	$4.7B	2.32%
157	Adapthealth Corp	AHCO:US	Health Care	$824M	2.28%
158	Alvotech	ALVO:US	Health Care	$2.1B	2.19%
159	Privia Health Group Inc	PRVA:US	Health Care	$2.7B	2.03%
160	Dentsply Sirona Inc	XRAY:US	Health Care	$1.8B	1.96%
161	ICU Medical Inc	ICUI:US	Health Care	$4.0B	1.93%
162	MiMedx Group Inc	MDXG:US	Health Care	$682M	1.91%
163	Lumexa Imaging Holdings, Inc. Common Stock	LMRI:US	Health Care	$1.0B	1.88%
164	Bausch + Lomb Corp	BLCO:TO	Health Care	$8.8B	1.83%
165	MiniMed Group, Inc. Common Stock	MMED:US	Health Care	$5.5B	1.73%
166	RadNet Inc	RDNT:US	Health Care	$5.6B	1.70%
167	Harvard Bioscience Inc	HBIO:US	Health Care	$38M	1.58%
168	Omnicell Inc	OMCL:US	Health Care	$1.6B	1.52%
169	Pacira BioSciences, Inc.	PCRX:US	Health Care	$1.5B	1.48%
170	Repligen Corporation	RGEN:US	Health Care	$11.0B	1.40%
171	Theravance Biopharma Inc	TBPH:US	Health Care	$884M	1.33%
172	AtriCure Inc	ATRC:US	Health Care	$2.9B	1.25%
173	ICON PLC	ICLR:US	Health Care	$12.7B	0.97%
174	MannKind Corp	MNKD:US	Health Care	$1.1B	0.79%
175	Certara Inc	CERT:US	Health Care	$1.4B	0.77%
176	InnovAge Holding Corp	INNV:US	Health Care	$1.2B	0.67%
177	iRhythm Technologies Inc	IRTC:US	Health Care	$3.5B	0.65%
178	Fortrea Holdings Inc.	FTRE:US	Health Care	$2.0B	0.58%
179	JIN MEDICAL INTERNATIONAL LTD. Ordinary Shares	ZJYL:US	Health Care	$164M	0.50%
180	Corcept Therapeutics Incorporated	CORT:US	Health Care	$13.1B	0.47%
181	Supernus Pharmaceuticals Inc	SUPN:US	Health Care	$2.5B	0.39%
182	Quidel Corporation	QDEL:US	Health Care	$920M	0.38%
183	CanadaBis Capital Inc	CANB:V	Health Care	$2M	0.38%
184	BioLife Solutions Inc	BLFS:US	Health Care	$1.9B	0.26%
185	Amotiv Limited	AOV:TO	Health Care	$577M	0.21%

Frequently Asked Questions

Which Canadian company ranks #1 by roa (ttm) in Health Care?

As of October 14, 2026, Aspire BioPharma, Inc. (ASBP:US) ranks #1 in Health Care at 60.58%.

How often is this ranking updated?

The table is rebuilt from live fundamentals throughout the day. This page currently shows data as of October 14, 2026.

How many companies are in this roa (ttm) list?

This view shows 185 Canadian listings in Health Care. Canadian Depositary Receipts are hidden by default.

What is the difference between TSX and TSXV?

The Toronto Stock Exchange (TSX) lists larger established companies. The TSX Venture Exchange (TSXV) lists earlier-stage companies. Use the exchange filter to separate them.